Product Description: SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD[1].
Applications: Cancer-Kinase/protease
Formula: C17H17F3N2O3
References: [1]Gammons MV, et al. Topical antiangiogenic SRPK1 inhibitors reduce choroidal neovascularization in rodent models of exudative AMD. Invest Ophthalmol Vis Sci. 2013 Sep 5;54(9):6052-62.
CAS Number: 848057-98-7
Molecular Weight: 354.32
Compound Purity: 99.87
Research Area: Others
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)