SR-717, CAS 2375421-09-1

Product Description: SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity[1].

Applications: Cancer-programmed cell death

Formula: C15H8F2LiN5O3

References: [1]Emily N Chin, et al. Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science. 2020 Aug 21;369(6506):993-999.

CAS Number: 2375421-09-1

Molecular Weight: 351.19

Compound Purity: 99.89

Research Area: Cancer; Inflammation/Immunology

Solubility: DMSO : 10 mg/mL (ultrasonic)/Methanol : 3.33 mg/mL (ultrasonic)

Target: STING

• SKU: MEXHY-131454-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-131454-10
• Package Unit: 10 mg
• Quantity Unit: STK