SR1664, CAS 1338259-05-4

Product Description: SR1664 is a PPARγ antagonist. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50=80 nM; Ki= 28.67 nM)[1][2].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C33H29N3O5

References: [1] Marciano DP, Kuruvilla DS, Boregowda SV, et al. Pharmacological repression of PPARγ promotes osteogenesis. Nat Commun. 2015;6:7443. Published 2015 Jun 12./[2]Choi JH, et al. Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation. Nature. 2011;477(7365):477-481. Published 2011 Sep 4.

CAS Number: 1338259-05-4

Molecular Weight: 547.60

Compound Purity: 98.0

Research Area: Metabolic Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PPAR

• SKU: MEXHY-12483-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12483-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK