Src Kinase Inhibitor I, CAS 179248-59-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine

Purity: ≥98%

Formula Markup: C22H19N3O3

Formula Weight: 373.4

CAS Number: 179248-59-0

Notes: The Src kinases constitute a family of non-receptor tyrosine kinases, which includes Src and Lck. Src kinase inhibitor I is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.{23054,17331} It less effectively blocks the receptor tyrosine kinases VEGFR2 and C-fms (IC50 = 0.32 and 30 µM), as well as a long list of serine/threonine kinases.{23054,17331} Src kinase inhibitor I also inhibits receptor-interacting protein-2 with an IC50 value of 26 nM.{17331}

• SKU: CAY14592-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 14592-5
• Package Unit: 5 mg
• Quantity Unit: STK