Product Description: SRI-011381 is an orally active TGF-β signaling agonist, exhibits neuroprotective effects[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C20H31N3O
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References: [1]Jingyin Han, et al. The Improvement Effect of Sodium Ferulate on the Formation of Pulmonary Fibrosis in Silicosis Mice Through the Neutrophil Alkaline Phosphatase 3 (NALP3)/Transforming Growth Factor-β1 (TGF-β1)/α-Smooth Muscle Actin (α-SMA) Pathway. Med Sci Monit. 2021 Jun 15;27:e927978./[2]Qian Wu, et al. Astrocytic YAP protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model through TGF-β signaling. Theranostics. 2021 Jul 25;11(17):8480-8499.
CAS Number: 1629138-41-5
Molecular Weight: 329.48
Compound Purity: 99.58
Research Area: Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: TGF-beta/Smad
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