SRT 3025 (hydrochloride), CAS 2070015-26-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 5-(3-methoxypropyl)-2-phenyl-N-[2-[6-(1-pyrrolidinylmethyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]-4-thiazolecarboxamide, monohydrochloride

Purity: ≥98%

Formula Markup: C31H31N5O2S2 / HCl

Formula Weight: 606.20298

CAS Number: 2070015-26-6

Notes: SRT 3025 is an activator of sirtuin 1 (SIRT1).{61587,61588,61589} It increases SIRT1 levels in, and inhibits RANKL-induced osteoclastogenesis of, mouse bone marrow-derived macrophages (BMDMs) when used at a concentration of 2 µM.{61587} SRT 3025 inhibits the proliferation of SU.86.86 pancreatic adenocarcinoma cells (IC50 = 0.98 µM).{61588} It decreases plasma levels of LDL, VLDL, and total cholesterol in ApoE-/- mice fed a high-cholesterol diet when administered at a dose of 3.18 g/kg.{61589}

• SKU: CAY34420-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34420-100
• Package Unit: 100 mg
• Quantity Unit: STK