Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: N1,N8-dihydroxy-octanediamide
Purity: ≥98%
Formula Markup: C8H16N2O4
Formula Weight: 204.2
CAS Number: 38937-66-5
Notes: Suberohydroxamic acid (SBHA) is a competitive histone deacetylase (HDAC) inhibitor that has been shown to inhibit HDAC1 (IC50 = 0.25 μM) and HDAC3 (IC50 = 0.30 μM).{17174} SBHA causes cell differentiation, cell cycle arrest, or apoptosis.{18561,18558,18559,18557,18556} HDAC inhibitors, including SBHA, act synergistically to kill cancer cells when used in combination with cytostatic drugs, allowing lower doses of both inhibitors and drugs to be used.{18560,18446}