Target Synonym: Sulfotransferase 2A;Sult2a;Bile Salt Sulfotransferase;Dehydroepiandrosterone Sulfotransferase;DHEAS;DHEA-ST;Hydroxysteroid Sulfotransferase;ST2;ST2A1;ST2A3;Sulfotransferase 2A1;HST;STD;SULT2A1;Alcohol/hydroxysteroid sulfotransferase;Bile salt sulfotranasferase 2A1;dehydroepiandrosterone-preferring;DHEA ST;DHEA sulfotranasferase;EC 2.8.2.14;hSTa;member 1;sulfotranasferase;Sulfotransferase family 2A;Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1
Background: Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.
Immunogen: Recombinant Human SULT2A1 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000;
Calculated MW: 34 kDa
Observed MW: 35 kDa
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