SX-682, CAS 1648843-04-2

Product Description: SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].

Applications: Cancer-programmed cell death

Formula: C19H14BF4N3O4S

References: [1]Sun L, et al. Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy. JCI Insight. 2019 Apr 4;4(7)./[2]Lu X, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017 Mar 30;543(7647):728-732. 

CAS Number: 1648843-04-2

Molecular Weight: 467.20

Compound Purity: 99.67

Research Area: Cancer; Inflammation/Immunology; Endocrinology

Solubility: DMSO : 200 mg/mL (ultrasonic)

Target: CXCR

• SKU: MEXHY-119339-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-119339-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK