T-10418, CAS 1608784-68-4

Product Description: T-10418 is an agonist for G2 accumulation protein (G2A) (also known as G protein-coupled receptor GPR132) with an EC50 of 0.82 μM. T-10418 exhibits a sensitizing effect on mouse primary sensory neurons. T-10418 exhibits good pharmacokinetic characteristics, and no obvious toxicity (at 100 μM) in mouse models[1].

Applications: Neuroscience-Neuromodulation

Formula: C22H20N2O4

References: [1]Hernandez-Olmos V, et al., Development of a Potent and Selective G2A (GPR132) Agonist. J Med Chem. 2024 Jun 25.

CAS Number: 1608784-68-4

Molecular Weight: 376.41

Compound Purity: 99.78

Research Area: Neurological Disease

Target: G2A (GPR132)

• SKU: MEXHY-163763-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163763-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK