Tafamidis meglumine, CAS 951395-08-7

Product Description: Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis[1].

Applications: Neuroscience-Neuromodulation

Formula: C21H24Cl2N2O8

Citations: Vascul Pharmacol. 2024 Jul 17:107411./J Med Chem. 2021 Sep 21.

References: [1]Bulawa CE, et al. Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9629-34.

CAS Number: 951395-08-7

Molecular Weight: 503.33

Compound Purity: 99.79

Research Area: Neurological Disease

Solubility: DMSO : 12.5 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL

Target: Transthyretin (TTR)

• SKU: MEXHY-14852A-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14852A-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK