TAK-653, CAS 1358751-06-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 9-[4-(cyclohexyloxy)phenyl]-3,4- dihydro-7-methyl-pyrazino[2,1-c][1,2,4]thiadiazine, 2,2-dioxide

Purity: ≥98%

Formula Markup: C19H23N3O3S

Formula Weight: 373.47034

CAS Number: 1358751-06-0

Notes: An AMPA receptor positive allosteric modulator; increases glutamate-induced calcium influx in CHO cells expressing human AMPA receptors (EC50 = 3.3 µM); potentiates AMPA receptor-mediated currents in rat primary hippocampal neurons (EC50= 4.4 µM); ameliorates MK-801-induced working memory deficits in the radial arm maze task in rats from 0.1-10 mg/kg; increases DMTS accuracy in cynomolgus monkeys at 0.06 mg/kg

• SKU: CAY42187-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42187-5
• Package Unit: 5 mg
• Quantity Unit: STK