Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (3ß,18a,19a)-urs-20(30)-en-3-ol, 3-acetate
Purity: ≥95%
Formula Markup: C32H52O2
Formula Weight: 468.75408
CAS Number: 6426-43-3
Notes: Taraxasterol acetate is a pentacyclic triterpene that has been found in P. sagittalis and has diverse biological activities.{64678,64679} It reduces the production of reactive oxygen species (ROS) and Hsp72 induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in isolated human neutrophils when used at concentrations of 10 and 100 µM and increases Hsp72 production in unstimulated isolated human neutrophils at 100 µM.{64678} Taraxasterol acetate (50 µg/ml) reduces protein levels of the E3 ubiquitin ligase RNF31 and increases levels of the autophagy marker LC3-I/II in HCT116 and SW480 cells.{64679} Topical administration of taraxasterol acetate (46 µg/ear) reduces ear edema induced by arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607), croton oil, or PMA in mice.{64678}
English
Deutsch
