Tauroursodeoxycholate (dihydrate), CAS 117609-50-4

Product Description: Tauroursodeoxycholate (Tauroursodeoxycholic acid; TDUCA) dihydrate is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK[1][2].

Applications: Cancer-Kinase/protease

Formula: C26H49NO8S

References: [1]Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16./[2]Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345.

CAS Number: 117609-50-4

Molecular Weight: 535.73

Compound Purity: 99.86

Research Area: Cancer

Solubility: DMSO : 83.33 mg/mL (ultrasonic)

Target: Apoptosis;Caspase;Endogenous Metabolite;ERK

• SKU: MEXHY-19696B-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-19696B-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK