TBOPP, CAS 1996629-79-8

Product Description: TBOPP is a selective inhibitor of DOCK1 with an IC50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with high affinity (Kd of 7.1 μM), has anti-tumor activity for broader types of tumors[1].

Applications: Cancer-programmed cell death

Formula: C24H21F3N2O4S

References: [1]Tajiri H, et al. Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1. Cell Rep. 2017 May 2;19(5):969-980.

CAS Number: 1996629-79-8

Molecular Weight: 490.49

Compound Purity: 99.96

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: DOCK

• SKU: MEXHY-124711-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-124711-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK