TC ASK 10, CAS 1005775-56-3

Product Description: TC ASK 10 (Compound 10) is a potent, selective and orally active apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 of 14 nM. The inhibitory activities of TC ASK 10 towards other representative panel of kinases are less than 50%, except for ASK2 (IC50 of 0.51 μM)[1].

Applications: Cancer-Kinase/protease

Formula: C21H23Cl2N5O

References: [1] Terao Y, et al. Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7326-9.

CAS Number: 1005775-56-3

Molecular Weight: 432.35

Compound Purity: 99.84

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Apoptosis;MAP3K

• SKU: MEXHY-103258-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103258-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK