TC-S 7005, CAS 1082739-92-1

Product Description: TC-S 7005 is a Polo-like kinases (Plks) inhibitor with IC50s of 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively[1].

Applications: COVID-19-anti-virus

Formula: C21H17N3O3

References: [1]Hanan EJ, et al. Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9./[2]Stephan Reinhard Künzel, et al. Hypoxia-induced epigenetic silencing of polo-like kinase 2 promotes fibrosis in atrial fibrillation. bioRxiv 445098

CAS Number: 1082739-92-1

Molecular Weight: 359.38

Compound Purity: 99.68

Research Area: Inflammation/Immunology; Cardiovascular Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Polo-like Kinase (PLK)

• SKU: MEXHY-108597-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108597-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK