TCMDC-135051, CAS 2413716-15-9

TCMDC-135051, CAS 2413716-15-9
SKU
MEXHY-126323-25
Packaging Unit
25 mg
Manufacturer
MedChemExpress

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Product Description: TCMDC-135051 is a highly selective and potent protein kinase PfCLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC50=320 nM)[1].

Applications: COVID-19-immunoregulation

Formula: C29H33N3O3

References: [1]Alam MM, et al. Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target. Science. 2019 Aug 30;365(6456). pii: eaau1682.

CAS Number: 2413716-15-9

Molecular Weight: 471.59

Compound Purity: 99.90

Research Area: Infection

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Parasite
More Information
SKU MEXHY-126323-25
Manufacturer MedChemExpress
Manufacturer SKU HY-126323-25
Package Unit 25 mg
Quantity Unit STK
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