TCS 46b, CAS 302799-86-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-2H-benzimidazol-2-one

Purity: ≥98%

Formula Markup: C22H23N3O

Formula Weight: 345.4

CAS Number: 302799-86-6

Notes: An antagonist of NR1A/2B subunit-containing NMDA receptors (IC50 = 0.0053 µM); selective for NMDA receptors containing NR1A/2B subunits over NMDA receptors containing NR1A/2A and NR1A/2C subunits (IC50s = 35 and >100 µM, respectively); inhibits L-DOPA-induced contralateral rotations in a rat model of 6-OHDA-induced Parkinson's disease at 10 mg/kg; has been radiolabeled and used as an NR1A/2B-selective PET radiotracer

• SKU: CAY42123-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42123-5
• Package Unit: 5 mg
• Quantity Unit: STK