Product Description: TD-198946, a thienoindazole derivative, is a potent chondrogenic agent.
Applications: COVID-19-immunoregulation
Formula: C27H22N4O3S
References: [1]Yano F, et al. A novel disease-modifying osteoarthritis drug candidate targeting Runx1. Ann Rheum Dis. 2013 May;72(5):748-53./[2]Yano F, et al. Disease-modifying effects of TD-198946 on progressed osteoarthritis in a mouse model. Ann Rheum Dis. 2014 Nov;73(11):2062-4./[3]Yano F, et al. Cell-sheet technology combined with a thienoindazole derivative small compound TD-198946 for cartilage regeneration. Biomaterials. 2013 Jul;34(22):5581-7./[4]Kobayashi M, Chijimatsu R, Hart DA, et al. Evidence that TD-198946 enhances the chondrogenic potential of human synovium-derived stem cells through the NOTCH3 signaling pathway. J Tissue Eng Regen Med. 2021;15(2):103-115.
CAS Number: 364762-86-7
Molecular Weight: 482.55
Compound Purity: 99.93
Research Area: Inflammation/Immunology
Solubility: DMSO : ≥ 28 mg/mL
Target: Others
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