TDG Polyclonal Antibody

Target Synonym: TDG;hTDG

Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Background: The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.

Immunogen: Recombinant fusion protein of human TDG

Dilution: WB 1:500-1:2000

Calculated MW: 46kDa

Observed MW: 50KDa

• SKU: ELSE-AB-92674-120
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: E-AB-92674-120
• Package Unit: 120μL
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit
• Conjugate: Unconjugated