Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
Purity: ≥98%
Formula Markup: C17H15FN6O3
Formula Weight: 370.338043
CAS Number: 856866-72-3
Notes: Tedizolid is an oxazolidinone antibiotic and active metabolite of the antibiotic tedizolid phosphate (Item No. 23729).{59752} Tedizolid phosphate is converted to tedizolid by phosphatases in vivo. It is active against a wide variety of clinical isolates, including isolates of methicillin-resistant S. aureus (MRSA), E. faecalis, and penicillin-susceptible S. pneumoniae (MICs = 0.5, 0.5, and 0.25 µg/ml, respectively), as well as isolates of anaerobic bacteria (MICs = 0.25-4 µg/ml). Tedizolid protects against mortality in a mouse model of systemic methicillin-susceptible S. aureus (MSSA) infection (ED50 = 8.8 mg/kg).{59753}
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