Product Description: Tegatrabetan (BC2059) is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1)[1].
Applications: Cancer-programmed cell death
Formula: C28H36N4O6S2
References: [1]Fiskus W, et al. Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells. Leukemia. 2015 Jun;29(6):1267-78.
CAS Number: 1227637-23-1
Molecular Weight: 588.74
Compound Purity: 99.77
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)