Tempo, CAS 2564-83-2

Product Description: Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells[1][2][3][4].

Applications: Cancer-Kinase/protease

Formula: C9H18NO

References: [1]Chen X, et al. Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling. Br J Cancer. 2020 May 5./[2]Kaur G, et al. Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol Carcinog. 2010 Mar;49(3):290-301./[3]Guo X, et al. Comparative Genotoxicity of TEMPO and 3 of Its Derivatives in Mouse Lymphoma Cells. Toxicol Sci. 2018 May 1;163(1):214-225.

CAS Number: 2564-83-2

Molecular Weight: 156.25

Compound Purity: 99.92

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: DNA/RNA Synthesis;Mitochondrial Metabolism;Reactive Oxygen Species

• SKU: MEXHY-W001187-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W001187-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK