TERT activator-1, CAS 666699-46-3

Product Description: TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). TERT activator-1 promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. TERT activator-1 promotes adult neurogenesis and enhances neuromuscular function. TERT activator-1 reduces cellular senescence and systemic inflammation in aged mice, and can be used in the study of aging[1].

Applications: COVID-19-immunoregulation

Formula: C14H12ClF2NO2S

References: [1]Shim HS, et al. TERT activation targets DNA methylation and multiple aging hallmarks. Cell. 2024 Jul 25;187(15):4030-4042.e13.

CAS Number: 666699-46-3

Molecular Weight: 331.77

Compound Purity: 99.50

Research Area: Inflammation/Immunology; Neurological Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: AP-1;ERK;MEK

• SKU: MEXHY-402361-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-402361-50
• Package Unit: 50 mg
• Quantity Unit: STK