TH10785, CAS 1002801-51-5

Product Description: TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β, δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases and aging connected with DNA oxidative lesions[1].

Formula: C17H21N3

References: [1]Maurice Michel, et al. Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science. 2022 Jun 24;376(6600):1471-1476.

CAS Number: 1002801-51-5

Molecular Weight: 267.37

Compound Purity: 99.93

Research Area: Cancer; Metabolic Disease

Solubility: DMSO : ≥ 100 mg/mL

Target: Others

• SKU: MEXHY-147313-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-147313-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK