Product Description: Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1].
Applications: Cancer-programmed cell death
Formula: C26H34N2O7
References: [1]Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.