Clone Name: 21G7
Application Note: WB: 1:500 - 1:1000. ELISA: 1:1000 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 126
Specificity/Sensitivity: This antibody recognizes human Tie2 in western blot without cross reactivity with human Tie1.
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Uniprot ID: Q02763
Antigen Species: Human
Immunogen: hTie2 extracellular domain
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: TEK receptor tyrosine kinase
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