Tilfrinib, CAS 1600515-49-8

Product Description: Tilfrinib (compound 4f) is a potent and selective Brk/PTK6 inhibitor with an IC50 value of 3.15 nM for Brk. Tilfrinib shows good anti-proliferative activity and has potential of anti-tumour[1][2].

Applications: Cancer-Kinase/protease

Formula: C17H13N3O

References: [1]Mahmoud KA, et al. Discovery of 4-anilino α-carbolines as novel Brk inhibitors. Bioorg Med Chem Lett. 2014 Apr 15;24(8):1948-51./[2]Zhang Q, Liu S, et al. ETV4 mediated tumor-associated neutrophil recruitment promotes lymphangiogenesis and lymphatic metastasis of bladder cancer[J]. 2022.

CAS Number: 1600515-49-8

Molecular Weight: 275.30

Compound Purity: 99.69

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: BRK

• SKU: MEXHY-110244-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-110244-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK