Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (OC-6-13)-dichloro[7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-?N21,?N22,?N23,?N24]-stannate(2-), dihydrogen
Purity: ≥95%
Formula Markup: C34H34Cl2N4O4Sn / 2H
Formula Weight: 754.2896
CAS Number: 106344-20-1
Notes: Heme oxygenases (HOs) convert protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin (Item No. 17161). Tin mesoporphyrin IX is a potent, competitive inhibitor of HO activity in vitro (Ki = 14 nM).{30698} It inhibits hepatic, renal, and splenic HO activity in vivo for extended periods of time.{30698} Tin mesoporphyrin IX blocks bilirubin production in vivo, decreasing HO activity in animal models of hyperbilirubinemia.{30698,26672,30699} Tin mesoporphyrin IX can be used to study the physiological roles of induced HO-1 expression in animal models.{30697,30700,30701}
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