Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 2-hydroxy-N-(5-nitro-2-thiazolyl)-benzamide-3,4,5,6-d4
Purity: ≥99% deuterated forms (d1-d4)
Formula Markup: C10H3D4N3O4S
Formula Weight: 269.27064
CAS Number: 1246817-56-0
Notes: Tizoxanide-d4 is intended for use as an internal standard for the quantification of tizoxanide (Item No. 13693) by GC- or LC-MS. Tizoxanide is an active metabolite of the antiparasitic nitazoxanide (Item No. 13692).{17926} Tizoxanide is formed from nitazoxanide via deacetylation of nitazoxanide in the stomach. It is active against M. tuberculosis (MIC = 16 µg/ml). It also reduces the growth of the disease-causing parasites L. mexicana and T. cruzi in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM), and inhibits hepatitis B and hepatitis C virus replication (EC50 = 0.15 μM for both).{19984,19985,19983}
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