TK216, CAS 1903783-48-1

Product Description: TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor[1]. TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity[2].

Applications: Neuroscience-Neuromodulation

Formula: C19H15Cl2NO3

References: [1]Brian Lannutti, et al. Uses of indolinone compounds. US10159660B2./[2]Spriano F, et al. The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents. Clin Cancer Res. 2019 Aug 15;25(16):5167-5176.

CAS Number: 1903783-48-1

Molecular Weight: 376.23

Compound Purity: 99.84

Research Area: Cancer

Solubility: DMSO : ≥ 250 mg/mL

Target: DNA/RNA Synthesis

• SKU: MEXHY-122903-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-122903-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK