TLR7/8 agonist 1 (dihydrochloride), CAS 1620278-72-9

Product Description: TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline[1][2].

Applications: COVID-19-immunoregulation

Formula: C22H27Cl2N5

References: [1]Shukla NM, et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6384-6./[2]Beesu M, et al. Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity. J Med Chem. 2015 Oct 8;58(19):7833-49.

CAS Number: 1620278-72-9

Molecular Weight: 432.39

Compound Purity: 99.70

Research Area: Inflammation/Immunology

Solubility: DMSO : 83.33 mg/mL (ultrasonic)

Target: Toll-like Receptor (TLR)

• SKU: MEXHY-103698A-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103698A-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK