TNF RI/TNFRSF1A, Mouse (HEK293, Fc)

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Product Description: TNFRSF1A (TNF RI) protein has a high abilityto bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 targetgene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediateapoptosis, and function as a regulator of inflammation. TNF RI/TNFRSF1A Protein,Mouse (HEK293, Fc) is expressed by HEK 293 cells and has a transmembrane region with a Fc tag at the C-terminus[1].

Formula: 21937(Gene_ID)P25118 (M1-A212)(Accession)

References: [1]WajantH, et, al. Tumor necrosis factor signaling. Cell Death Differ. 2003Jan;10(1):45-65./[2]FuQ, et, al. miR-29a up-regulation in AR42J cells contributes to apoptosis viatargeting TNFRSF1A gene. World J Gastroenterol. 2016 May 28;22(20):4881-90./[3]Zhou S, et, al. Bioinformatics AnalysisIdentifies TNFRSF1A as a Biomarker of Liver Injury in Sepsis TNFRSF1A is aBiomarker for Septic Liver Injury. Genet Res (Camb). 2022 Oct 15;2022:1493744./[4]EgusquiaguirreSP, et, al. The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway inBreast Cancer Cells. Neoplasia. 2018 May;20(5):489-498.

Molecular Weight: Approximately 55 kDa

Compound Purity: 92.0

• SKU: MEXHY-P73449-10UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P73449-10UG
• Package Unit: 10 μg
• Quantity Unit: STK