Tofacitinib metabolite-1, CAS 1640971-51-2

Product Description: Tofacitinib metabolite-1 is a metabolite of Tofacitinib, a JAK inhibitor. Tofacitinib metabolite-1 can be used in the pharmacokinetics and metabolism studies of tofacitinib[1][2].

Formula: C16H20N6O2

References: [1]Martin E Dowty, et al. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans. Drug Metab Dispos. 2014 Apr;42(4):759-73./[2]Matthias Gehringer, et al. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres. ChemMedChem. 2014 Nov;9(11):2516-27.

CAS Number: 1640971-51-2

Molecular Weight: 328.376

Compound Purity: 99.59

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Drug Metabolite

• SKU: MEXHY-136336-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136336-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK