Tolazoline (hydrochloride), CAS 59-97-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4,5-dihydro-2-(phenylmethyl)-1H-imidazole, monohydrochloride

Purity: ≥95%

Formula Markup: C10H12N2 / HCl

Formula Weight: 196.7

CAS Number: 59-97-2

Notes: Tolazoline is an α1-adrenergic receptor (α1-AR; IC50 = 3,200 nM) and α2-AR antagonist (Kis = 112, 1,230, 354, and 173 nM for α2A, α2B-, α2C-, and α2D-ARs, respectively).{52937,30610} Tolazoline inhibits α-AR agonist-induced contractions in isolated human corpus cavernosum smooth muscle (IC50 = 0.1 µM).{52935} It also lowers vascular resistance in isolated perfused porcine skin flaps (IPPSFs) preconstricted by norepinephrine with an EC50 value of 288 nM.{52936} Formulations containing tolazoline have been used in veterinary medicine to reverse the analgesia and sedation induced by xylazine in horses.

• SKU: CAY18865-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18865-25
• Package Unit: 25 g
• Quantity Unit: STK