Tolnaftate, CAS 2398-96-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-methyl-N-(3-methylphenyl)-carbamothioic acid, O-2-naphthalenyl ester

Purity: ≥98%

Formula Markup: C19H17NOS

Formula Weight: 307.4

CAS Number: 2398-96-1

Notes: Tolnaftate is a thiocarbamate antifungal agent.{53200} It is active against clinical isolates of the dermatophytes T. rubrum, T. mentagraphytes, T. verrucosum, E. floccosum, and M. canis (MIC50s = 50, 100, 6, 50, and 50 ng/ml, respectively), as well as 18 additional yeast and filamentous fungi species (MIC = 0.003-0.8 µg/ml).{17905},{25586} Tolnaftate also reduces aflatoxin production in A. parasiticus in a concentration-dependent manner.{53199} It inhibits squalene epoxidase with an IC50 value of 12.5 µg/ml in a cell-free assay.{53200}

• SKU: CAY21446-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21446-5
• Package Unit: 5 g
• Quantity Unit: STK