Torkinib (Standard), CAS 1092351-67-1

Product Description: Torkinib (Standard) is the analytical standard of Torkinib. This product is intended for research and analytical applications. Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor with an IC50 of 8 nM[1]. PP242 inhibits both mTORC1 and mTORC2 with IC50s of 30 nM and 58 nM, respectively[2].

Formula: C16H16N6O

References: [1]Apsel B, et al. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9./[2]Feldman ME, et al. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. PLoS Biol. 2009 Feb 10;7(2):e38.

CAS Number: 1092351-67-1

Molecular Weight: 308.34

Research Area: Cancer

Target: Apoptosis;Autophagy;Mitophagy;mTOR;Reference Standards

• SKU: MEXHY-10474R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10474R-0
• Package Unit: Get quote
• Quantity Unit: STK