Tosyl Phenylalanyl Chloromethyl Ketone, CAS 402-71-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl-benzenesulfonamide

Purity: ≥98%

Formula Markup: C17H18ClNO3S

Formula Weight: 351.8

CAS Number: 402-71-1

Notes: Tosyl phenylalanyl chloromethyl ketone (TPCK) is an irreversible inhibitor of chymotrypsin-like proteases that has been shown to affect cell proliferation, apoptosis, and tumorigenesis.{33079} It can disrupt PDK1 signaling to the AGC kinases, Akt, S6K1, and RSK, as well as MSK1 and MSK2.{33078} TPCK also inhibits superoxide production and suppresses neutrophil respiratory burst.{33080}

• SKU: CAY20166-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 20166-100
• Package Unit: 100 mg
• Quantity Unit: STK