Tranexamic Acid-13C2,15N, CAS 1292837-95-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: trans-4-(amino-15N-methyl-13C)-cyclohexanecarboxylic-13C acid

Purity: ≥95%

Formula Markup: C6[13C2]H15[15N]O2

Formula Weight: 160.2

CAS Number: 1292837-95-6

Notes: Tranexamic acid 13C2,15N is intended for use as an internal standard for the quantification of tranexamic acid (Item No. 19193) by GC- or LC-MS. Tranexamic acid is an inhibitor of fibrinolysis that inhibits the interaction of plasmin with fibrin (IC50 = 3.1 µM in isolated human plasma).{31118} It reduces increases in the expression of the profibrogenic genes Timp1 and Col1a1, but not Itgb6, Tgfβ1, or Tgfβ2, and increases in hepatic protein levels of cytokeratin 19 (CK19) and type I collagen induced by α-naphthylisothiocyanate (AINT) after 28 days in a mouse model of chronic bile duct injury.{45512}

• SKU: CAY28804
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 28804-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: GC-MS, LC-MS, Isotopenmarkierung