Trimetrexate (glucuronate) (Standard), CAS 82952-64-5

Product Description: Trimetrexate (glucuronate) (Standard) is the analytical standard of Trimetrexate (glucuronate). This product is intended for research and analytical applications. Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia[1][2].

Formula: C25H33N5O10

References: [1]R C Jackson, et al. Biochemical pharmacology of the lipophilic antifolate, trimetrexate. Adv Enzyme Regul. 1984;22:187-206./[2]P J Harris, et al. Trimetrexate glucuronate associated with anti-Kaposi sarcoma effect. AIDS Patient Care STDS. 1996 Oct;10(5):280-1.

CAS Number: 82952-64-5

Molecular Weight: 563.56

Research Area: Cancer; Infection

Target: Antifolate;Bacterial;Reference Standards

• SKU: MEXHY-103396R-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103396R-0
• Package Unit: Get quote
• Quantity Unit: STK