Product Type: Agonist
CAS No.: 97322-87-7
MolecularFormula: C24H27NO5S
Molecular Weight: 441,54
Source: Synthetic
Purity: >98%
Solubility: Soluble to 100 mM in DMSO and to 10 mM in ethanol
Appearance: White solid
PubChem CID: 5591
Scientific Background: Troglitazone, a member of the thaizolidinediones, is an anti-diabetic and anti-inflammatory drug. It works by activating peroxisome proliferator-activated receptors (PPARs) (1). It is a ligand to both PPARalpha and gamma. It also contains an alpha-tocopheroyl moiety, potentially giving it vitamin E like activity (which helps in inflammation) (2).
References: 1. Lambe K.G. and Tugwood J.D. (1996) Eur J Biochem. 239(1): 1-7.2. Aljada A., et al. (2001) J Clin Endocrinol Metab. 86(7): 3250-3256.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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