Tucidinostat, CAS 1616493-44-7

Product Description: Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9[1].

Applications: Cancer-programmed cell death

Formula: C22H19FN4O2

References: [1]Ning ZQ, et al. Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity. Cancer Chemother Pharmacol. 2012 Apr;69(4):901-9.

CAS Number: 1616493-44-7

Molecular Weight: 390.41

Compound Purity: 98.60

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)/Ethanol : 1 mg/mL (ultrasonic;warming;heat to 60°C)

Target: HDAC

• SKU: MEXHY-109015-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-109015-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK