TXNRD1 Monoclonal Antibody

Target Synonym: TRXR;TXNRD;TXNRD1;GRIM-12;TR;TR1;TRXR1;TXNR;GRIM12;KDRF

Background: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 0' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

Immunogen: Recombinant Human TXNRD1 protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: ICC/IF 1:20-1:100;FCM 1:25-1:100;

• SKU: ELSAN200069P-100
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: AN200069P-100
• Package Unit: 100μL
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunofluorescence, Flow Cytometry, Immunocytochemistry
• Isotype: IgG1
• Host: Mouse
• Conjugate: Unconjugated