TYRA-300, CAS 2800223-30-5

Product Description: TYRA-300 is an orally active, selective inhibitor for FGFR3 with an IC50 of 11 nM in Ba/F3. TYRA-300 exhibits antitumor efficacy against urothelial cancers and solid tumors[1].

Formula: C25H24Cl2N6O3S

References: [1]Hudkins RL, et al., Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia. J Med Chem. 2024 Sep 26;67(18):16737-16756.

CAS Number: 2800223-30-5

Molecular Weight: 559.47

Compound Purity: 99.90

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: FGFR

• SKU: MEXHY-159642-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-159642-10
• Package Unit: 10 mg
• Quantity Unit: STK