Application Note: WB: 1:500-1:2000. ICC/IF: 1:100-1:500. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 60
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium Azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Uniprot ID: P14679
Antigen Species: Human
Immunogen: A synthesized peptide derived from human TYR(Accession P14679), corresponding to amino acid residues A481-L529.
Conjugation: Unconjugated
Full Name: tyrosinase
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