TZ9, CAS 1002789-86-7

TZ9, CAS 1002789-86-7
SKU
CAY15964-10
Packaging Unit
10 mg
Manufacturer
Cayman Chemical

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Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-amino-6-(phenylamino)-2-(4-nitrobenzoate)-1,3,5-triazine-2-methanol

Purity: ≥98%

Formula Markup: C17H14N6O4

Formula Weight: 366.3

CAS Number: 1002789-86-7

Notes: TZ9 is a cell-permeable triazine compound that inhibits the human E2 ubiquitin-conjugating enzyme Rad6B.{26248} TZ9 selectively docks to the Rad6B catalytic site, inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular β-catenin, induces G2/M arrest and apoptosis, and inhibits proliferation and migration of metastatic human breast cancer cells (IC50 = 6 µM).{26248}
More Information
SKU CAY15964-10
Manufacturer Cayman Chemical
Manufacturer SKU 15964-10
Package Unit 10 mg
Quantity Unit STK
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