Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4-amino-6-(phenylamino)-2-(4-nitrobenzoate)-1,3,5-triazine-2-methanol
Purity: ≥98%
Formula Markup: C17H14N6O4
Formula Weight: 366.3
CAS Number: 1002789-86-7
Notes: TZ9 is a cell-permeable triazine compound that inhibits the human E2 ubiquitin-conjugating enzyme Rad6B.{26248} TZ9 selectively docks to the Rad6B catalytic site, inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular β-catenin, induces G2/M arrest and apoptosis, and inhibits proliferation and migration of metastatic human breast cancer cells (IC50 = 6 µM).{26248}