Target Synonym: UBE2M;UBC-RS2;UBC12;hUbc12
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of human UBE2M
Dilution: WB 1:200-1:2000
Calculated MW: 20kDa
Observed MW: 21kDa