Product Description: UBP 1112 is a selective group III mGluR antagonist, with a Kd of 5.1 μM.UBP 1112 shows 96-fold affinity for group III over group II mGlu receptor (Kd, 488 μM), and shows no significant activity at group I mGlu receptor or iGlu receptor[1].
Formula: C10H14NO5P
References: [1]Miller JC, et al. Phenylglycine derivatives as antagonists of group III metabotropic glutamate receptors expressed on neonatal rat primary afferent terminals. Br J Pharmacol. 2003 Aug;139(8):1523-31.
CAS Number: 339526-74-8
Molecular Weight: 259.20
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: mGluR