Product Description: UCB9608 is a potent, selective and orally active PI4KIIIβ inhibitor, with an IC50 of 11 nM, selective over PI3KC2 α, β, and γ lipid kinases. UCB9608 improves metabolic stability and exhibits excellent pharmacokinetic profile, acts as a potent immunosuppressive agent[1].
Applications: COVID-19-immunoregulation
Formula: C20H26N8O2
References: [1]Reuberson J, et al. Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo. J Med Chem. 2018 Aug 9;61(15):6705-6723.
CAS Number: 1616413-96-7
Molecular Weight: 410.47
Compound Purity: 99.59
Research Area: Inflammation/Immunology
Solubility: DMSO : 65 mg/mL (ultrasonic)
Target: PI4K